Cosmelan by Mesoesetetic® is the world’s leading treatment program that brightens and evens skin tone while preventing their reappearance. With an exclusive combination of active ingredients, Cosmelan acts as an enzyme in the melanocyte to correct and regulate the production of melanin.
This inhibits the activation of tyrosinase and reduces the amount of melanin synthesised for skin that is visibly clearer, brighter and more radiant. The complete programme includes an intense in-clinic treatment which is then supported with a home skincare regime.
Not sure if this is the treatment for you?
How does Cosmelan work?
The Cosmelan® formula contains an exclusive combination of active ingredients with proven efficacy, which act on all stages of the hyperpigmentation process to completely eliminate existing hyperpigmentations, preventing both their reappearance and the appearance of new dark spots.
Cosmelan® works at two levels: At the first level by inhibiting the activation of tyrosinase inside the melanosome, reducing the oxidative stress, and thereby reducing melanin synthesis; at a second level, by containing copper chelators (Cu2+) tyrosinase function is reduced. Cosmelan® acts by blocking the transfer of the melanosome to the keratinocytes, thereby preventing movement of the pigment to the superficial layers of the skin.
It acts by reducing the amount of melanin synthesized, reducing the intensity of the dark spot. It also acts on the stratum corneum, stimulating the renewal of the epidermis and intensively eliminating the accumulation of melanin.
More About Cosmelan
Is Cosmelan a Skin Peel?
Although often referred to as a Skin Peel, the Cosmelan treatment goes beyond a peel. Unlike peels, which act on the surface of the problem, Cosmelan gets to the root of the problem.
It consists in a treatment that visibly removes and attenuates pigmentation spots (like a peel) while exerting a regulating action that corrects the overproduction of pigmentation and prevents the spots from reappearing.
What type of pigmentation does Cosmelan treat?
Cosmelan can treat all types of pigmentations derived from the over-production of melanin which may have been triggered by hormones, sun exposure, genetics or scarring. Cosmelan effectively treats melasma, post-inflammatory hyper-pigmentation (PIH), and freckles (sun spots).
When is the best time to receive a Cosmelan treatment?
Cosmelan may be performed anytime of the year if you are able to ensure the treated area is not exposed to long periods of intense sun exposure. Ideally, the autumn and winter months are the most advisable time for treatment due to this requirement.
However in instances when sun exposure cannot be avoided, greater care and the use of a very high sunscreen, such as Melan 130 Pigment Control to be applied liberally and the time spent outdoors to be kept an absolute minimum.
How long is the treatment period for the entire Cosmelan course?
To achieve the greatest results, we strongly encourage all clients to adhere to a strict post-treatment regimine for up to 6 months depending on the severity of the initial pigmentation.
When will you see results?
The most significant changes occur in the first few weeks, you should see an improvement in skin texture and a noticeable decrease in pigmentation. This can give a misleading feeling of success.
During this period melanin has been removed from the outermost skin layers, and therefore we see the pigmentation much more faded and the skin smoother and softer, but the origin of the problem has not been controlled yet.
The melanocyte, a cell where melanin is produced, is still uncontrolled and continues to produce pigment (melanin) in excess. To control this overproduction, it is important to continue a home treatment with regulating action to prevent the pigmentation from reappearing.
What happens if I stop applying the home treatment?
If you do not follow the home regimen, you are interrupting the treatment and will therefore not obtain the expected results. Not applying Cosmelan 2 depigmenting cream with regulating action involves not regulating the melanocyte and, therefore, a persistent uncontrolled, excessive production of melanin. The spot will reappear as the skin layers are renewed, as melanin migrates to the surface making the spot increasingly evident.
Not using photoprotection, Melan 130 Pigment Control, involves a very high risk that the spot returns, as skin is more sensitive and receptive to external aggressions during the treatment.
Can I combine the cosmelan method with other depigmentation treatments?
During at least the first three months of the method, it is not recommended to use any other type of minimally invasive treatment that can cause a skin lesion, as well as peels, microneedling, exfoliations, etc., as it can even cause repigmentation. It is advisable to use soothing and regenerating treatments both in clinic and at home in case it is needed.
Does the treatment make me unable to fulfil my daily life activities normally?
As it is not an invasive treatment, it does not make you unable to fulfil your activities of daily living normally. Caution must be exerted when fulfilling some type of activities during the first days, a skin adaptation period after the cabin treatment. For instance, it is advisable to avoid bathing in swimming pools, prolonged sun exposure and activities that involve excessive sweating.
Can the pigmentation return after the end of treatment?
After your professional in-clinic treatment, excess pigmentation can be removed visibly. However, it is a dynamic process, where the imbalance forming them can cause their recurrence. Therefore, even if the spots are not seen, it is essential to apply a daily regulatory depigmentation treatment and photoprotection throughout the year to prevent repigmentation.
Does the cosmelan® treatment have side effects?
When used correctly and under the supervision of your Skin Specialist, there should be no side effects.
Cosmelan is a topical treatment, therefore minimally invasive, that does not prevent you from following your normal daily life. During the initial phase and following the treatment, the skin may become irritated or show redness.
This is totally normal and expected, and it will disappear within a few days. During the home phase, it is common to experience slight peeling and sensitivity, which are symptoms that disappear when applying the home products recommended by your Skin Specialist.
What is the difference between Cosmelan and Dermamelan?
Both are depigmentation treatments that produce excellent results, but Cosmelan is an aesthetic treatment, whereas Dermamelan is a treatment that requires a doctor's supervision and monitoring.
Dermamelan is not performed at The Skin Boutique and we always advise all clients to consider more conservative approaches to their skin concerns as more intense treatments inherently have more risk and should only be considered when the benefits of the treatment outweigh these potential risks.